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Side effects : Rash, dizziness and excessive sleepiness which tends to improve over time

an FDA-approved active ingredient that works directly on the central nervous system by activating melanocortin receptors in the brain, unlike approaches that target the vascular system

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Fractionation of this sleep-promoting blood eventually yielded a small nine-amino acid peptide that could reproduce these effects, and Monnier and colleagues published their findings in 1977, entering the compound into the scientific literature as Delta Sleep-Inducing Peptide