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It is important to note that, in patients with long-standing diabetes and insufficient insulin secretory capacity, the glucose-lowering efficacy of GLP-1 RA is likely to be reduced as a result of diminished incretin effects, and concomitant basal insulin treatment may be required [53]
The fact that the FDA defined copies much more broadly strongly suggests that the state boards narrow interpretation based on the form of the API, i.e., base vs
GLP-1 receptor agonist use and cancer risk in obese nondiabetic adults. Annals of Oncology
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