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Inhibition of NNMT has been explored in preclinical research for potential effects on adiposity regulation, insulin sensitivity, and metabolic efficiency

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[30] For example, cyanocobalamin can be converted to its analog cobalamins via reduction to B 12s , followed by the addition of the corresponding alkyl halides, acyl halides, alkene or alkyne

Kuipers MT, Thang HD, Arntzenius AB