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Prior to use, the lyophilized FOXO4-DRI peptide must be dissolved using high-purity Bacteriostatic Water

As the mRNA expression of Fxr and Tgr5 was not altered by either T3 or MB07811 (Supplementary Fig

Data availability The Cancer Therapeutics Response Portal (CTRP, V2.1) is a web-based publicly accessible database ( The data generated in this study are provided in the Supplementary Information/Source Data file

These drugs belong to a class known as incretin mimetics, which mimic the action of natural hormones in the body involved in metabolic regulation

Clinical trials have shown weight loss of approximately 12-15% of body weight with semaglutide and 5-8% with liraglutide over 12-18 months when combined with lifestyle modifications