A clinical trial found that thymosin beta 4 applied topically helped to accelerate wound healing.[ref] Other studies show that it accelerates wound healing by up to a month faster than without TB4.[ref] Dry eyes: Eye drops containing thymosin beta 4 were trialed in a multicenter, randomized, double-masked, placebo-controlled 56-day phase 2 clinical trial including a 28-day follow-up at 2 US sites
Once p53 is freed, it moves out of the nucleus toward the mitochondria and sets off the intrinsic apoptosis pathway (a caspase-driven self-destruct program)
In some embodiments, the otic formulation or composition comprises about 0.04% by weight of the cholesterol
In some embodiments, the ear is the outer ear
Injection site reactions Redness, mild swelling, itching, or small nodules at the injection site occurred in 5 to 15% of trial participants