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DNA methylation is associated with gene silencing, while hypomethylation is involved with the stimulation of the transcription process (Triantaphyllopoulos et al., 2016) ( Figure 1 )

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8, 9, 10, 11, 12 these patients and experimental animals have a diminished antioxidant status, 13 which contributes to the accumulating evidence that increased vascular oxidative stress could be involved in the pathogenesis of essential hypertension

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