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Potential Effects Studied Promotes lipolysis (breakdown of stored fat) May reduce lipogenesis (formation of new fat) Generally does not significantly increase IGF-1 levels Appears to have fewer growth-promoting effects than full HGH in research models Has been investigated primarily for weight management and body-fat reduction

Metabolic adaptation on and off the medication Mike Haney: What do we know about coming back to the concept of metabolic adaptation

[DOI] [PubMed] [Google Scholar] 20.Emmanuele V., Lpez L.C., Berardo A., Naini A., Tadesse S., Wen B., DAgostino E., Solomon M., DiMauro S., Quinzii C., et al

Hepatology 64(6):20282037 Wachsmuth HR, Weninger SN, Duca FA (2022) Role of the gutbrain axis in energy and glucose metabolism