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In the US, the Food and Drug Administration (FDA) has warned that some patients are turning to unapproved versions of GLP-1 drugs, including semaglutide and tirzepatide, for weight loss

As a result, the existing recommendations on how to dose this compound largely stem from animal studies and anecdotal reports

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Patients experiencing new or worsening skin symptoms should monitor their response carefully and seek appropriate medical guidance to ensure safe continuation of therapy