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GLP-1 RAs enhance the expression of glucose transporters in tissues sensitive to insulin, leading to increased glucose uptake and improved regulation of blood glucose levels
These companies will need to understand how their demand may be impacted in the future, which part of their markets will be most affected, how their portfolio could evolve to mitigate the impact and how they can establish themselves as complementary to GLP-1RAs
GLP-1 RAs are safe concerning the risk of medullary thyroid cancer
Abstract Incretin-based therapies with glucagon-like peptide-1 receptor agonists (GLP-1RA) are already established in the treatment of type 2 diabetes (T2D)
It activates GLP-1, GIP and glucagon receptors to influence appetite, metabolism and energy expenditure, making it one of the most closely studied investigational weight management therapies
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