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Hirsch SR, Kory RC

After 6 weeks, the collagen-treated subjects showed significant improvements in skin wrinkle parameters and skin moisturization, but the supplement did not significantly modify skin firmness or elasticity

PubMed PMID: 3662416

Therefore, drugs can be selected on the basis of the expression pattern of ferroptosis-inducing genes (e.g., SLC7A11, GSH, and GPX) or genes associated with metabolic pathways that affect ferroptosis (e.g., GLUT, PDK4, glutaminase, VDAC, and G6PD)

In terms of the immune response, our secretome analysis revealed enrichment of immune-related pathways under oxidative stress, with qPCR confirming increased expression of inflammatory mediators IL-6, IL-11, and IL-18 shortly after H 2 O 2 treatment