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10.1016/j.jpba.2025.117121 15 JinL.XiaoJ.LuoY.DuanL.GongY.LiY.et al (2025)

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Your Overall Health Underlying health conditions, such as gastrointestinal disorders (like Crohns disease, celiac disease, or atrophic gastritis) that impair nutrient absorption, or certain medications you may be taking, can influence how your body absorbs and utilizes B12

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Important safety considerations include the risk of acute pancreatitis (seek urgent medical attention for severe, persistent abdominal pain), gallbladder disease, and potential worsening of diabetic retinopathy, particularly in patients with pre-existing retinopathy who experience rapid improvement in blood glucose control