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For patients at higher risk, alternative therapies should be considered, and if tirzepatide is prescribed, close monitoring with a lower starting dose and slower titration schedule may be appropriate

In contrast to small molecules, biologics are made from or with living systems such as microorganisms, cells, proteins, sugars, nucleic acids, tissues, or complex combinations of these

Bariatric surgery can effectively resolve Type 2 diabetes by enhancing insulin sensitivity and reducing the need for diabetes medications

If you notice any unusual skin changes, rashes, or increased sensitivity to sunlight after starting tirzepatide, document these changes with photographs if possible and discuss them with your healthcare provider to determine whether they are related to the medication or require further investigation

References: Summary of Revisions: Standards of Care in Diabetes2026