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10.1042/bst20230122 140 ZwebenJ

Conversely, nicotine may exert paradoxical inhibitory effects by activating immune pathways and inducing apoptosis, such as through stimulation of immature dendritic cells via PI3K/Akt signaling and modulation of caspase-3 and Cyclin B1 expression through 7-nAChR signaling [36]

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A number of pathologies have been characterized by an unbalanced cysteinome profile, including cystinuria, renal calculi, Huntington's disease, and Alzheimer's disease (68)