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350 Mitochondrial dysfunction in Schwann cells triggers alterations in lipid metabolism, leading to myelin sheath dysfunction and accumulation of toxic lipid intermediates, which cause axonal degeneration and neuropathy

Serotonin Preservation through Antioxidant and Anti-inflammatory Action NACs significant antioxidant properties are crucial for mitigating the impact of oxidative stress in CNS [111]

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Glutathione plays a central role in antioxidant defenses, and irreversible cell damage supervenes when the cell is unable to maintain intracellular glutathione concentrations

Compared with Abs of the IgG1 subclass, IgG4 Abs have a limited ability to bind to immune effector molecules [256]