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doi: 10.1016/j.ebiom.2020.103147

J Inflammation Res

How does exercise affect glutathione levels

GSTp (the main isoform of erythrocytes) [218] has been found to be competitively inhibited by hemin with a low Ki (10 7 M), suggesting GST has an active role inside RBCs potentially as a hemin-binding protein [219]

In a chronic social defeat stress model in mice, 21 days of oral administration at 0.1 mg/kg corrected depressive-like behavior, restored motor activity with a therapeutic effect of 60 percent, completely recovered anhedonia, restored synaptophysin levels (74 percent therapeutic effect), and fully restored CREB levels in the hippocampus