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Examples of such signaling proteins that can be influenced directly or indirectly by ROS modifications include MAPK (ERK, JNK, p38), IKB/NFB, PI3K/AKT, IP 3 R/Ryanodine receptor, and the NLRP3 inflammasome 90,92,93,94 (Fig

In summary, growing evidence underscores that gut microbiota dysbiosis plays a pivotal role in both the development and outcome of ischemic stroke through immune, barrier, and metabolic pathways, suggesting that restoring gut microbial balance could become an essential strategy for stroke prevention and recovery

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When you read the rest of this guide, anchor back to that line

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