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The most common side effects of Rybelsus include: Nausea Diarrhea Vomiting Constipation Abdominal pain Decreased appetite The most common side effects of Ozempic include: Nausea Vomiting Diarrhea Loss of appetite Constipation Stomach pain Effectiveness for blood sugar control and reducing hemoglobin a1c levels Both Rybelsus and Ozempic are effective at reducing HbA1c levels, a key marker for blood sugar control in people with type 2 diabetes

Among the observational studies 39,45,46,49,50,51 comprised by the meta-analyses, two are worth a separate mention

These mechanisms can lead to reduced food and fluid intake, as well as gastrointestinal symptoms that may affect hydration status