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Fwu CW, Eggers PW, Kirkali Z2, McVary KT, Burrows PK, Kusek JW
10.1210/en.2003-1112 Endocrinology 110 RinaldiS.PeetersP
Women with a first-degree relative diagnosed before age 50 have at least a twofold increased risk of developing breast cancer ( Obesity Obesity, reflected by a high body mass index (BMI), is associated with an increased risk of breast cancer in postmenopausal women, whereas this association is not observed in premenopausal women ( Oral contraceptives Use of oral contraceptives is linked to a slight rise in breast cancer risk, which diminishes over time after cessation, with negligible risk ten years post-use
When administered to rats with carbon tetrachloride-induced liver fibrosis, roflumilast increased liver function while reducing inflammation and fibrosis markers
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