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A GSK3 is involved in the modulation of important intracellular signaling pathways, among them the pathway of protein kinase B (PKB/Akt), which is responsible for regulating cell survival, and the Wnt signaling pathway, which is involved in numerous cellular processes, including apoptosis and cell proliferation [22]

BMC Cancer (2016) 16:629

A new study found GLP-1 medications may help lower mortality risk for people who have colon cancer, a type of colorectal cancer

Ligand specificity GLP-2 and GLP-1 share high sequence similarity (69.7%) and have almost identical residues in two regions: the N-terminus (first six residues in GLP-2) that penetrates into the TMD core, and the C-terminus (residues 1833) that is recognized by the ECD and ECL1 of the receptor

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