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The highest incidence of nausea and vomiting occurred during dose escalation phases

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In the intestinal mucosa, this mechanism of action supports the enzymatic activity of glutathione-S-transferase, which plays a role in deconjugation at the site of the mucosa without the necessity for GSH uptake

Ipamorelin appears to act via the molecular mimicry of the natural hormone ghrelin, which triggers and stimulates the release of the growth hormone