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The challenge is to develop animal models that accurately account for these variables relevant to alcoholic patients

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Research Use Only: These products are intended for laboratory research use only

The isolated fraction induced delta-wave (slow-wave) sleep when injected into recipient animals giving the peptide its name and initiated one of the most distinctive research trajectories in neuropeptide biology: a compound with a clearly demonstrated biological name-property, an exceptionally wide pharmacological activity profile, and nearly five decades later a receptor that remains formally uncharacterised

To test this hypothesis, further experiments were conducted in the kidneys of diabetic mice, as well as in HG-treated HRMC cells