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Alendronate is excreted renally over 72 hours after a dose, and renal tubular handling of bisphosphonates involves organic anion transport pathways

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Jan 1 2018;187(1):60-74

NAM and streptozotocin (STZ)-induced T2DM also leads to hepatic damage, including disrupted antioxidant status, aberrant intrahepatic lipid accumulation, and inflammation

if you look at a lot of studies, and honestly, Andrew, I think a lot of the reason for conflicting data is because people are measuring plasma omega-3 levels