However, even with precursors, the body still has to do the work of assembly
Based on my experience and conversations with other athletes, here is a decision framework: Microdosing may be right if you: Only need to lose 3-8kg to reach your target race weight Train at high volume (10+ hours/week) and cannot afford to compromise fueling Have a history of GI sensitivity during exercise Are preparing for a specific race and cannot risk GI disruption Want to use GLP-1 as a tool alongside an already-disciplined nutrition plan Standard dosing may be more appropriate if you: Have significant weight to lose (15kg+) and are not currently in peak training Are in an off-season or base-building phase with lower fueling demands Have tried microdosing without meaningful results after 8-12 weeks Have metabolic health concerns (pre-diabetes, insulin resistance) that require therapeutic doses The key principle: find the minimum effective dose for your situation
If your provider identifies B12 deficiency despite your compounded formulation, they may prescribe additional B12 supplementation, either through separate injections, high-dose oral supplements (1000 mcg daily, which can overcome absorption limitations through passive diffusion), or sublingual formulations
When smoke exposure is high, I typically recommend 2 capsules, three times per day (morning, afternoon, and early evening, away from food) for a day or two until relief kicks in
Patients should instructed to report palpitations or feelings of a racing heartbeat while at rest
