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These recommendations are very consistent with the key points from the most current international guidelines, especially those published, in 2024 and 2025, by multi-society groups in both the US and the UK 1-3
In the SURPASS clinical trial program evaluating tirzepatide for type 2 diabetes and the SURMOUNT trials for weight management, insomnia was not identified as a statistically significant adverse event compared to placebo groups, based on published trial results
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It reduces the treatment burden and improves long-term compliance
Comparison of the effect of glucose-lowering agents on the risk of atrial fibrillation: A network meta-analysis
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