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This description of a case of MIC-S, complicated by Reye's syndrome, resulted in a good clinical response after management and is unprecedented in the literature

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The rationale is that GLP-1 agonists can affect B12 absorption over time, and supplementing directly in the injection ensures adequate levels

However, PGE2 is known to play a dual role, as it can both suppress the immune response against M.tb and protect the host from excessive inflammation, suggesting that NSAIDs should be exercised with caution for TB treatment [128]