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IL-37b, a unique member of the IL-1 family, may inhibit lesion growth by regulating proliferation, invasion, angiogenesis, and inflammation through the AKT and ERK1/2 signaling pathways (55)

The consumption of high-calorie/high-fat ultra-processed foods by children and adolescents is strongly associated with obesity [31,32] and obesity, in turn, is associated with chronic OxS [25]

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Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells

doi: 10.1073/pnas.1016217108 114 HegerMvan GolenRFBroekgaardenMMichelMC