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The most commonly reported early symptoms include a noticeable reduction in appetite within 24 to 72 hours, mild fullness or bloating after meals, slight nausea, particularly if eating large or fatty meals, and changes in bowel habits such as softer stools or mild constipation

Dec 18 2008;359(25):2707-2718

Relationship between disruption of the unstirred mucus layer and intestinal restitution in loss of gut barrier function after trauma hemorrhagic shock

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When to Seek Medical Help for Injection Reactions Contact your prescribing provider if injection site rashes develop signs of infection, including increasing pain, warmth beyond the immediate injection zone, pus drainage, or red streaking extending up your arm or leg