Resveratrol Activate Genes That Promote Resilience Against Stress (AKA Stress Response/Longevity Genes) Plants produce phytochemicals (like resveratrol) under stress These compounds either attract pollinators or in some cases, deter insects In humans, phytochemicals activate a variety of stress response pathways, resulting in many beneficial effects such as: The activation of SIRT1, which is linked to anti-inflammatory activity, metabolic adaptations, and neurological protection The activation AMP-kinase, a fuel-sensing enzyme that inhibits mTOR, leading to the down-regulation of cellular growth pathways Resveratrol and Exercise 250 mg/day of resveratrol blunted the positive effects of exercise in elderly men (aged 60-72) who exercised by engaging in cycling and CrossFit 3x/week for 8 weeks (Study) Which positive effects
Curcumin attenuates IR-induced myocardial injury by activating SIRT3
Tumor-related signaling pathways in ferroptosis NRF2 The nuclear factor-erythroid factor 2-related factor 2 (NRF2) signaling pathway is an important defense mechanism against ferroptosis, which needs to be activated to exert its antioxidant properties
BPC 157 mixing calculator: why dilution changes the draw volume People sometimes call this a BPC 157 mixing calculator because the mix choices change the concentration
It is no coincidence that melatonin, in addition to having a plethora of beneficial effects, executes neuroprotection by modulating mPTP activity 49,50
