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The Optimal Exercise Split Based on current evidence for preserving lean mass during pharmaceutical weight loss, the ideal exercise distribution is: Resistance Training: 2-4 sessions per week, 30-50 minutes each Cardiovascular Exercise: 2-3 sessions per week, 20-45 minutes each at moderate intensity Daily Movement: 7,000-10,000 steps daily through walking and general activity Total Weekly Exercise Time: 3-5 hours including all activities This distribution prioritizes muscle preservation through resistance training while providing adequate cardiovascular stimulus and daily movement without overtraining