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Glutathione (GSH) is a key intracellular antioxidant that scavenges excess reactive oxygen species (ROS) 22,23,24 , and it is an important molecule for the regulation of lymphocytes activation 25,26,27
doi: 10.1016/S0753-3322(03)00043-X
Its exact mechanism of action is unknown, but it is a potent antioxidant and seems to work to maintain the extracellular matrixs structural integrity, which is usually affected by ultraviolet radiation [88, 89]
Although uterine expression levels of estrogen receptor , G protein-coupled estrogen receptor, and steroid synthase were upregulated in the high-dose group, the decreased expression of connexin 43 and alkaline phosphatase as well as the increased expression of insulin-like growth factor-binding protein three and monoamine oxidase were consistent with decreased estrogen signaling and lower uterine weights