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Favorable Metabolic Effects GLP-1R agonists has shown to reduce the effects of several atherosclerotic cardiovascular disease (ASCVD) metabolic risk factors including diabetes mellitus, hyperlipidemia, overweight and obesity, and hepatic steatosis [68]

However, our current understanding likely represents a small proportion of the potential of the gut microbiota to impact metabolic homeostasis via gutbrain signaling, and this is a field that needs to continue to be explored

PQQ, as an auxiliary factor, can promote mitochondrial regeneration in aging cells, increase the activity of related enzymes, and stimulate mitochondrial growth

However, in our study, the combined use of these drugs restored SREBP2 expression but significantly reduced the expression levels of GLUT1/6

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