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In general, the 3.0 and 4.5 g/d groups exhibited dramatically greater rates of DEC compared with baseline while the 1.5 g/d dosage resulted in greater resistance to fatigue on sprints 1 and 2 with more modest changes in DEC with sprints 3 -5

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This delivery method is said to improve absorption and enhance effectiveness

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The combination protocols produce larger, more sustained pulses through dual receptor activation, with a comparable safety profile and often comparable cost when stacked