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(10) However, the positive effects of obesity on bone formation are nullified by the simultaneous induction of functional osteopenia, in a phenomenon known as the obesity paradox

In one study, the target dose was 2.4 mg once weekly

Data availability The source data for the findings of this study are available from the corresponding author upon reasonable request

Conversely, statins also exert beneficial mitochondrial effects, such as reducing mtDNA damage in atherosclerotic plaques and improving endothelial mitochondrial function via upregulation of eNOS