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consulting fees from Boehringer Ingelheim, GSK and Otsuka and speaking fees from Amgen and Sanofi (Mexico), but has not received funding in relation to the writing of this article

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In addition, the basal GLP-1 secretion was significantly inhibited by 1-M pasireotide treatment in GLUTag cells, and the inhibitory effect of pasireotide was reversed by PTX treatment (Fig