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Eight weeks of exposure to WD at middle-age increased brain cytokines in a sex-dependent manner, in which females demonstrated increased inflammation in the amygdala in response to WD, whereas males trended towards increased levels in the ventral hippocampus

This phenomenon overlaps closely with what is widely known as Ozempic Face . Who Is More Likely to Experience Ozempic Teeth

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Incompletely established adverse effect profile : Although Phase 2 trial data (NEJM, 2023) provides some safety information, the full adverse effect profile of retatrutide has not yet been established through the complete Phase 3 programme