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These may include: ( 4 ) Fatigue or lack of energy Brain fog or trouble concentrating Irritability or mood swings Pale skin or shortness of breath Tingling in the hands and feet Difficulty walking or staggering Anemia Swollen or inflamed tongue A B12 deficiency in men may also contribute to low testosterone, weight gain, and poor exercise recoverymaking it a hidden factor in many mens health concerns

Vegetarians, vegans, the elderly, individuals who regularly consume alcohol, and people suffering from Crohns disease or celiac disease are at a higher risk of developing a vitamin B12 deficiency

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Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity