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10.1128/spectrum.00849-23 377 RanisavljevM.StajerV.TodorovicN.OstojicJ.CvejicJ

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In the central nervous system, release of hypothalamic gonadotropin-releasing hormone leads to, first, nocturnal and, later, more consistent pulsatile luteinizing hormone and follicle-stimulating hormone release from the pituitary gland, which respectively promote testosterone production and spermatogenesis by the testicles