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Glutathione (GSH in its reduced form) is a tripeptide made up of amino acids, being the main endogenous antioxidant produced mainly by the liver

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J Allergy Clin Immunol 124 : 990996

Recent advances in Nrf2 activators, such as synthetic triterpenoids and natural compounds, highlight the need for temporal precisionactivating Nrf2 early to preserve -cell function but avoiding chronic overexpression, which may promote cancer (Mohamadi et al., 2023)