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In MDA-MB-231 cells, CuPDTC induces calpain-dependent PARP1 cleavage and apoptosis, and this process is reversed by calpastatin (a calpain inhibitor) (Milacic et al., 2008)

doi:10.1016/0163-7258(83)90023-2

The peptide binds to this G-protein coupled receptor (GPCR) with high affinity and selectivity, triggering a cascade of intracellular signaling events distinct from other growth hormone secretagogues

A 2018 case report and literature review found that this supplement may cause liver toxicity, inflammation, and fibrosis