Originally developed at the University of Arizona in the 1990s, it has become one of the most studied melanocortin peptides in the world
Lower case p , l , t , and u refer to plasma, liver, tissue and urine respectively
Interesting outcomes from phase I/II clinical trial aimed at evaluating the feasibility and safety of brain injection of AAV vector for MPS IIIA and IIIB suggest that intraparenchymal delivery may constitute a realistic option for neuropathic MPS [37]
A Mendelian randomization study suggested higher GLP-1 receptor expression may associate with increased OCD risk (OR 2.30), but this does not directly implicate the drug
Gene Expression: Research shows GHK-CU affects expression of over 4,000 genes, resetting many to a more youthful expression pattern