Clobazam in solid state was rather stable (especially under visible radiation), but in the case of its solution, UV radiation caused significant decomposition (Souri et al
The lyophilized form should be allowed to come to room temperature in its sealed vial before opening to prevent moisture condensation that can accelerate degradation
In IS subtyping, RF performed best (accuracy: 89.2%, sensitivity: 88.4%, specificity: 94.1%, F1-score: 0.87, AUC: 0.92)
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Furthermore, the included studies were heterogeneous concerning the characteristics of patients and study design (2 of studies on L-carnitine supplementation have been performed in the setting of hemodialysis when carnitine metabolism is altered in uremia and the depletion of carnitine is expected 62 , 4 in diabetic/metabolic syndrome patients with dyslipidemia and 1 in hyperlipidemic patients)