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Clinical trials using combinations of CoQ10 with cross-linked hyaluronic acid (XL-HA) have shown enhanced treatment outcomes in DED patients, attributed to CoQ10s antioxidant effects and HAs inherent water retention and viscoelasticity properties, which are essential for repairing ocular tissues (Postorino et al., 2018
Other investigations (Shi et al., 2021
Notably, -endorphin has been found to exert substantial antidepressant effects by influencing dopamine neurons involved in motivation and pleasure [96]
3 Human clinical trials on dietary supplements and oocyte outcomes In human clinical trials, dietary interventions with methyl donors during FSH stimulation in women with PCOS have demonstrated significant benefits