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This process is critical for maintaining cellular energy homeostasis and overall metabolic function

Recent studies have shown that the gut microbiota plays an important role in these processes

Recent studies suggest that mitochondrial dysfunction, secondary to a disruption of carnitine homeostasis, may also play a role in the loss of nitric oxide (NO) signaling and the development of endothelial dysfunction associated with a variety of cardiovascular diseases [2]

Herein, this review provides current knowledge on the biological functions of carnitine, the multiple hit impact of carnitine on the NAFLD progression, and the downstream mechanisms

[59] The control group was given carnitine supplementation at 20 mg/kg/day, which resulted in increased plasma concentrations of total carnitine