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In atopic dermatitis mouse models, AES16-2M administration downregulated disease scores, ear thickness, serum IgE (a key marker of allergic disease), and TSLP

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[116] reported that animals lacking dendritic cell factor 1 displayed not only PD-associated behavioral changes but also significant alterations within their gut microbiome

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The views expressed in this review are those of the authors and do not necessarily reflect the statements, opinions, views, conclusions, or policies of the National Center for Advancing Translational Sciences, or the US government