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Pharmacological Research 172: 105807

The substantia nigra isnt traditionally considered a primary serotonergic center (that distinction belongs to raphe nuclei), yet BPC-157s consistent elevation of serotonin there suggests a unique therapeutic approach

Local (and systemic) estradiol can stimulate lesion production of PGE2, which can activate pain fibers, enhance neuronal invasion of lesions by stimulating production of NGF and other neurotrophins, and promote sprouting of nociceptors that contribute persistent inflammatory pain and inhibit neuronal apoptosis

A Role for Iron in an Ancient Carbonic Anhydrase

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