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[50] Oxidative stress is thought to be linked to certain cardiovascular disease, since oxidation of LDL in the vascular endothelium is a precursor to plaque formation

FBCM is currently considered to be the most common cause of vitamin B12 deficiency, caused by impairment in the release of the vitamin from food, commonly because of conditions such as gastritis, achlorhydria, gastrectomy, use of antacids, or proton pump inhibitors (PPIs), gastric atrophy in the elderly, and Helicobacter pylori infection (, )

doi 10.1371/journal.pone.0198046 91 MarottiVXuYBohns MichalowskiCZhangWDominguesIAmeraouiHet al