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Oxidative stress is a key driver of uneven pigmentation, triggering excess melanin production in localised areas

Liraglutide (the active ingredient in Saxenda and Victoza) and semaglutide (the active ingredient in Ozempic) are two of the most studied options, and while they work through the same pathway, they differ in dosing, potency, side effects, and the kind of support they offer over time

Transgender and non-binary individuals on gender-affirming hormone therapy should be aware of the potential for semaglutide to affect their hormonal balance indirectly

Tirzepatide is administered through a weekly injection, and users often report significant weight reduction when paired with lifestyle changes

Nowakowski, S