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Ischemiareperfusion injury: pathological process and mechanism During heat stress, superficial blood vessels dilate for heat dissipation, leading to significantly reduced blood perfusion to major visceral organs like the liver, causing vasoconstriction and ischemia

However, in the brain and serum, aluminum was detected both when oxaliplatin was injected and when oxaliplatin and GSH were co-administered, even though the amounts of aluminum were reduced when GSH was injected (Figure 8)

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