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While this might seem contradictory to our findings, it is important to note that increased antidepressant use does not necessarily equate to increased suicidal ideation or attempts

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For subcutaneous semaglutide, we suggest starting at the intermediary 0.5 mg once-weekly dose for 4 weeks before transitioning to the maximal therapeutic dose of 1 mg once weekly to help avoid adverse GI effects (Figure 2)

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