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the human antibodies of the present invention thus block VEGF angiogenic activity, but do not inhibit other beneficial actions of VEGF, mediated through VEGFRl , such as those on certain immune and bone cells

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For histological analysis, excised samples were fixed in 4% (w/v) neutral buffered formalin, embedded in paraffin and cut into 3 m slices for haematoxylin and eosin (H&E) staining or immunohistochemistry

The underlying mechanism was revealed to be greater insulin secretion with oral vs i.v

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